Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $258 | In Stock | |
5 mg | $642 | In Stock | |
10 mg | $913 | In Stock | |
25 mg | $1,370 | In Stock | |
50 mg | $1,850 | In Stock | |
100 mg | $2,500 | In Stock | |
500 mg | $4,900 | In Stock | |
1 mL x 10 mM (in DMSO) | $533 | In Stock |
Description | ASM-024, a potent nicotinic receptor agonist, is a small molecule synthetic piperazine compound that promotes different targets and signaling pathways of β2-adrenergic receptors mediating smooth muscle relaxation, and is a potential compound for the treatment of asthma and chronic obstructive bronchitis with anti-inflammatory activity. |
In vitro | Incubation of HBSMC cells with ASM-024 did not induce significant production of cAMP compared to salbutamol or formoterol treated cells.[1] Fifteen minutes of incubation of hBSMC with ASM-024 alone had no effect on [Ca2+]i. However, a 10 minute pre-treatment with ASM-024 decreased [Ca2+]i rise in cells challenged with 10-6 M histamine or methacholine.[1] |
In vivo | ASM-024 increased in vitro relaxation response to maximally effective concentration of short—acting beta-2 agonists in dog and human bronchi.[1] ASM-024 induces smooth muscle relaxation of β2-AR desensitized tracheas.[1] |
Molecular Weight | 233.37 |
Formula | C15H25N2 |
Cas No. | 1609534-88-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
Solubility Information | DMSO: 2.34 mg/mL (10.01 mM) ![]() | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.