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CK-666

CK-666
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Purity:99.33%
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CK-666

Catalog No. T10826Cas No. 442633-00-3
CK-666 is a cell-permeable inhibitor of the actin-related protein Arp2/3 complex, binding to and stabilizing its inactive state, thereby preventing the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) configuration.
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Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$79In Stock
10 mg$143In Stock
25 mg$296In Stock
50 mg$573In Stock
100 mg$795In Stock
200 mg$995In Stock
1 mL x 10 mM (in DMSO)$87In Stock
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Product Introduction

Bioactivity
Description
CK-666 is a cell-permeable inhibitor of the actin-related protein Arp2/3 complex, binding to and stabilizing its inactive state, thereby preventing the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) configuration.
Chemical Properties
Molecular Weight296.34
FormulaC18H17FN2O
Cas No.442633-00-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (421.81 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3745 mL16.8725 mL33.7450 mL168.7251 mL
5 mM0.6749 mL3.3745 mL6.7490 mL33.7450 mL
10 mM0.3375 mL1.6873 mL3.3745 mL16.8725 mL
20 mM0.1687 mL0.8436 mL1.6873 mL8.4363 mL
50 mM0.0675 mL0.3375 mL0.6749 mL3.3745 mL
100 mM0.0337 mL0.1687 mL0.3375 mL1.6873 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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