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CPTH2
🥰Excellent
Catalog No. T8344Cas No. 357649-93-5
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
CPTH2
🥰Excellent
Purity: 99.5%
Catalog No. T8344Cas No. 357649-93-5
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $31 | In Stock | |
| 2 mg | $44 | In Stock | |
| 5 mg | $72 | In Stock | |
| 10 mg | $113 | In Stock | |
| 25 mg | $192 | In Stock | |
| 50 mg | $289 | In Stock | |
| 100 mg | $455 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $125 | In Stock |
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Purity:99.5%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network. |
| In vitro | CPTH2 decreases cell viability, adhesion, and invasiveness in ccRCC cell line 786-O. It shows preferential inhibition for KAT3B-p300 with hypoacetilating effects on histone H3 at specific H3-K18. Immunohistochemical analysis of 70 ccRCC tumor tissues compared with peritumoral normal epithelium showed a statistical significant reduction of p300/H3AcK18 paralleled by an increase of H3AcK14 in G1 grade and an opposed trend during tumor progression to worst grades[1]. |
| Molecular Weight | 291.8 |
| Formula | C14H14ClN3S |
| Cas No. | 357649-93-5 |
| Smiles | Clc1ccc(cc1)-c1csc(NN=C2CCCC2)n1 |
| Relative Density. | 1.38 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (34.27 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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