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Results for "

ccrcc

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  • Inhibitor Products
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    TargetMol | Activity
  • Recombinant Protein
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    TargetMol | inventory
Crenigacestat
T36331421438-81-4
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor model, Crenigacestat inhibited expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment.
  • $56
In Stock
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TargetMol | Citations Cited
XPW1
T778102700286-66-2
XPW1 is a new potent and selective CDK9 inhibitor with antitumour activity that transcriptionally inhibits the DNA repair process in ccRCC cells.XPW1 can be used to study clear cell renal cell carcinoma.
  • $105
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TargetMol | Inhibitor Sale
HIF-1/2α-IN-1
T61442
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α. Its inhibitory effect on HIF-2α activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/2α-IN-1 has the ability to decrease HIF-1α levels. This compound is particularly valuable for research on clear cell renal cell carcinoma (ccRCC) [1].
  • $1,520
10-14 weeks
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CPTH2
T8344357649-93-5
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
  • $31
In Stock
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Belzutifan
T166791672668-24-4
Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
  • $64
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