Shopping Cart
- Remove All
Your shopping cart is currently empty
Crolibulin
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
Catalog No. T15012Cas No. 1000852-17-4
Select Batch
Purity:98.19%
Contact us for more batch information
Crolibulin
Catalog No. T15012Cas No. 1000852-17-4
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $35 | In Stock | |
| 5 mg | $83 | In Stock | |
| 10 mg | $137 | In Stock | |
| 25 mg | $238 | In Stock | |
| 50 mg | $355 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $92 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Crolibulin"
Methylene Blue trihydrate
T00067220-79-3
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate is used as a bacteriologic stain and as an indicator. It inhibits soluble guanylyl cyclase and has been used to treat cyanide poisoning and to lower levels of methemoglobin. It also inhibits tau filament formation (IC50: 1.9μM).
- $42
Size
QTY
Flubendazole
T000931430-15-6
Flubendazole (Flumoxane) is available OTC in Europe that is an anthelmintic using to treat worm infection in humans.
- $50
Size
QTY
Paclitaxel
Cited
T096833069-62-4
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
- $34
Size
QTY
CitedOxfendazole
T071453716-50-0
Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
- $34
Size
QTY
4-Isopropoxybenzoic acid
T2497713205-46-4
4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.
- $34
Size
QTY
Mebendazole Cited
T115531431-39-7
Mebendazole (Mebenvet) is a hedgehog inhibitor, used as an antihelminthic.
- $31
Size
QTY
CitedN-Phenylbenzylamine
T0651103-32-2
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
- $29
Size
QTY
4'-Demethylepipodophyllotoxin
T29376559-91-7
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
- $33
Size
QTY
Methylene Blue Cited
T688861-73-4
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
- $30
Size
QTY
CitedThiabendazole
T0938148-79-8
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
- $41
Size
QTY
Benproperine phosphate
T500719428-14-9
Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.
- $37
Size
QTY
T-900607
T68147261944-52-9In house
T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.
- $195
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
| Description | Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization. |
| Targets&IC50 | Tubulin polymerization:0.52 μM |
| In vitro | Crolibulin demonstrates notable cytotoxic effects on HT-29 cells, achieving an IC50 value of 0.52 μM[2]. It is effective against a range of experimental tumors and significantly inhibits mitosis during the G2/M phase[2]. |
| Alias | EPC2407 |
| Molecular Weight | 417.26 |
| Formula | C18H17BrN4O3 |
| Cas No. | 1000852-17-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 120 mg/mL (287.59 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Crolibulin | purchase Crolibulin | Crolibulin cost | order Crolibulin | Crolibulin chemical structure | Crolibulin in vitro | Crolibulin formula | Crolibulin molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.