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Decamethonium bromide
🥰Excellent
Catalog No. T0818Cas No. 541-22-0
Alias Syncurine, Decacuran
Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist.
Decamethonium bromide
🥰Excellent
Purity: 99.79%
Catalog No. T0818Alias Syncurine, DecacuranCas No. 541-22-0
Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $45 | In Stock |
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Purity:99.79%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist. |
| In vivo | At the motor neuromuscular endplate, Decamethonium induces a depolarization that prevents the normal release of acetylcholine from presynaptic terminals from acting further, thereby preventing the nerve stimulus from affecting the muscle. During binding, Decamethonium actually activates (depolarizes) the motor endplate, but does not degrade itself, so the cell membrane remains depolarized and unresponsive to normal acetylcholine release. As a depolarizing muscle relaxant or neuromuscular blocker, Decamethonium is used in anesthesia to induce paralysis. It has a short duration of action similar to that of acetylcholine and acts as a partial agonist at nicotinic acetylcholine-like receptors. |
| Alias | Syncurine, Decacuran |
| Molecular Weight | 418.29 |
| Formula | C16H38Br2N2 |
| Cas No. | 541-22-0 |
| Smiles | [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 77 mg/mL (184.1 mM) DMSO: 65 mg/mL (155.39 mM), Sonication is recommended.  Ethanol: 24 mg/mL (57.4 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO/H2O
DMSO/H2O
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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