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Dexpramipexole dihydrochloride
🥰Excellent
Catalog No. T11011Cas No. 104632-27-1
Alias R-(+)-Pramipexole dihydrochloride, KNS-760704 dihydrochloride, (R)-Pramipexole dihydrochloride
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
Dexpramipexole dihydrochloride
🥰Excellent
Purity: 99.88%
Catalog No. T11011Alias R-(+)-Pramipexole dihydrochloride, KNS-760704 dihydrochloride, (R)-Pramipexole dihydrochlorideCas No. 104632-27-1
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $44 | In Stock | |
| 10 mg | $72 | In Stock | |
| 25 mg | $155 | In Stock | |
| 50 mg | $263 | In Stock | |
| 100 mg | $397 | In Stock | |
| 200 mg | $582 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | In Stock |
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CitedSelect Batch
Purity:99.88%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist. |
| In vitro | Dextromethorphan has been found to have neuroprotective effects and is being studied for the treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptosis pathways, and improves cell survival in response to various neurotoxins and β-amyloid neurotoxicity. Compared with the S-(-) isomer, dextromethorphan has lower dopamine agonist activity. |
| Alias | R-(+)-Pramipexole dihydrochloride, KNS-760704 dihydrochloride, (R)-Pramipexole dihydrochloride |
| Molecular Weight | 284.25 |
| Formula | C10H19Cl2N3S |
| Cas No. | 104632-27-1 |
| Smiles | Cl.Cl.CCCNC1CCc2nc(N)sc2C1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (351.80 mM) H2O: 100 mg/mL (351.80 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
R-Pramipexole DihydrochlorideR-PramipexolePramipexole DihydrochloridePramipexoleKNS-760704 DihydrochlorideKNS760704 DihydrochlorideKNS-760704KNS760704KNS 760704 DihydrochlorideKNS 760704InhibitorinhibitDopamineReceptorDopamine ReceptorDexpramipexole dihydrochlorideDexpramipexole DihydrochlorideDexpramipexole(R)-Pramipexole
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