Eliapixant

Name: Eliapixant
Brand: TargetMol
SKU: T9519
Price: 135 USD
Availability: InStock
Rating: 5 (10 reviews)

Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.

Catalog No. T9519Cas No. 1948229-21-7

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Purity:98.65%

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COA LCMS HNMR

Eliapixant

Catalog No. T9519Cas No. 1948229-21-7

Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$135	In Stock
2 mg	$169	In Stock
5 mg	$228	In Stock
10 mg	$328	In Stock
25 mg	$538	In Stock
50 mg	$745	In Stock
100 mg	$993	In Stock
1 mL x 10 mM (in DMSO)	$243	In Stock

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Product Introduction

Bioactivity

Description	Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
Targets&IC50	P2X3:8 nM
In vivo	Eliapixant can be used in the study of coughs and diabetes complications[1].
Alias	BAY 1817080

Chemical Properties

Molecular Weight	478.49
Formula	C₂₂H₂₁F₃N₄O₃S
Cas No.	1948229-21-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 30 mg/mL (62.70 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0899 mL	10.4495 mL	20.8991 mL	104.4954 mL
5 mM	0.4180 mL	2.0899 mL	4.1798 mL	20.8991 mL
10 mM	0.2090 mL	1.0450 mL	2.0899 mL	10.4495 mL
20 mM	0.1045 mL	0.5225 mL	1.0450 mL	5.2248 mL
50 mM	0.0418 mL	0.2090 mL	0.4180 mL	2.0899 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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