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Eliapixant
🥰Excellent
Catalog No. T9519Cas No. 1948229-21-7
Alias BAY 1817080
Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
Eliapixant
🥰Excellent
Purity: 98.65%
Catalog No. T9519Alias BAY 1817080Cas No. 1948229-21-7
Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $135 | In Stock | |
| 2 mg | $169 | In Stock | |
| 5 mg | $228 | In Stock | |
| 10 mg | $328 | In Stock | |
| 25 mg | $538 | In Stock | |
| 50 mg | $745 | In Stock | |
| 100 mg | $993 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $243 | In Stock |
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Purity:98.65%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough. |
| Targets&IC50 | P2X3:8 nM |
| In vivo | Eliapixant can be used in the study of coughs and diabetes complications[1]. |
| Alias | BAY 1817080 |
| Molecular Weight | 478.49 |
| Formula | C22H21F3N4O3S |
| Cas No. | 1948229-21-7 |
| Smiles | C[C@@H](NC(=O)c1cc(O[C@@H]2CCOC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F |
| Relative Density. | 1.360 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (62.70 mM), Sonication and heating to 60℃ are recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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