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FAUC-365
FAUC-365 is a D3 dopamine receptor agonist.
Catalog No. T21667Cas No. 474432-66-1
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Purity:98.09%
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FAUC-365
Catalog No. T21667Cas No. 474432-66-1
FAUC-365 is a D3 dopamine receptor agonist.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $29 | In Stock | |
| 2 mg | $39 | In Stock | |
| 5 mg | $68 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $198 | In Stock | |
| 50 mg | $323 | In Stock | |
| 100 mg | $467 | In Stock | |
| 200 mg | $655 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $75 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | FAUC-365 is a D3 dopamine receptor agonist. |
| Targets&IC50 | 5-HT:0.50 nM(Ki) |
| In vitro | As a dichloro derivative, FAUC-365 revealed D3 affinities that were comparable to its methoxy-substituted analogs, however, the selectivities of FAUC-365 against 5HT-1A, 5-HT2, and R1 were substantially higher, which was demonstrated by the extraordinary selectivity ratios of 17600, 7200, 5200, and 680 over D1, D2long, D2short, and D4, respectively, were determined for FAUC-365 with Ki of 0.50 nM. In addition, the benzothiophene analog FAUC 346 and its oxa analog showed partial agonist character with EC50 values at 0.36 and 1.5 nM, respectively [1]. |
| Molecular Weight | 462.44 |
| Formula | C23H25Cl2N3OS |
| Cas No. | 474432-66-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: insoluble DMSO: 50 mg/mL (108.12 mM)  EtOH: insoluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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