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Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $45 | In Stock | |
1 g | $53 | In Stock | |
1 mL x 10 mM (in DMSO) | $48 | In Stock |
Description | Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium. |
In vivo | Hydroxyprogesterone caproate is administered to pregnant rats in order to assess the effect of intraperitoneal exposure to supranormal levels of hydroxyprogesterone caproate on the male reproductive potential in the first generation. The cauda epididymal sperm count and motility decrease significantly in rats exposed to hydroxyprogesterone caproate during embryonic development, when compared with control rats. The levels of serum testosterone decrease with an increase in follicle stimulating hormone and luteinizing hormone in adult rats exposed to hydroxyprogesterone caproate during the embryonic stage[2]. |
Alias | Primolut Depot, Hormofort, Delalutin, 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate |
Molecular Weight | 428.6 |
Formula | C27H40O4 |
Cas No. | 630-56-8 |
Smiles | CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O |
Relative Density. | 1.0148 g/cm3 (Estimated) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 50 mg/mL (116.66 mM), Sonication is recommended. Ethanol: 79 mg/mL (184.3 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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