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ICG-001

ICG-001
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Purity:99.55%
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ICG-001

Catalog No. T6113Cas No. 780757-88-2
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$108In Stock
25 mg$218In Stock
50 mg$379In Stock
100 mg$588In Stock
500 mg$1,260In Stock
1 mL x 10 mM (in DMSO)$78In Stock
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Product Introduction

Bioactivity
Description
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
Chemical Properties
Molecular Weight548.63
FormulaC33H32N4O4
Cas No.780757-88-2
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
2% DMSO+40% PEG300+5% Tween 80+53% Saline: 10 mg/mL (Sonification is recommended)
DMSO: 100 mg/mL (182.27 mM)
Ethanol: 9 mg/mL(16.4 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM1.8227 mL9.1136 mL18.2272 mL91.1361 mL
5 mM0.3645 mL1.8227 mL3.6454 mL18.2272 mL
10 mM0.1823 mL0.9114 mL1.8227 mL9.1136 mL
DMSO
1mg5mg10mg50mg
20 mM0.0911 mL0.4557 mL0.9114 mL4.5568 mL
50 mM0.0365 mL0.1823 mL0.3645 mL1.8227 mL
100 mM0.0182 mL0.0911 mL0.1823 mL0.9114 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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