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Lobeline hydrochloride

Lobeline hydrochloride
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Purity:99.65%
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Lobeline hydrochloride

Catalog No. T0268Cas No. 134-63-4
Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.
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Pack SizePriceAvailabilityQuantity
50 mg$46In Stock
100 mg$82In Stock
200 mg$97In Stock
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Product Introduction

Bioactivity
Description
Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.
Aliasα-Lobeline hydrochloride, L-Lobeline hydrochloride
Chemical Properties
Molecular Weight373.92
FormulaC22H27NO2·HCl
Cas No.134-63-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 45 mg/mL (120.35 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6744 mL13.3718 mL26.7437 mL133.7184 mL
5 mM0.5349 mL2.6744 mL5.3487 mL26.7437 mL
10 mM0.2674 mL1.3372 mL2.6744 mL13.3718 mL
20 mM0.1337 mL0.6686 mL1.3372 mL6.6859 mL
50 mM0.0535 mL0.2674 mL0.5349 mL2.6744 mL
100 mM0.0267 mL0.1337 mL0.2674 mL1.3372 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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