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Methyldopa hydrate

Methyldopa hydrate
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Methyldopa hydrate

Catalog No. T5954Cas No. 41372-08-1
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
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Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 g$48In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Product Introduction

Bioactivity
Description
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
AliasAlpha-Methyldopa Sesquihydrate, L-(-)-α-Methyldopa hydrate, MK-351 hydrate, Methyldopa Sesquihydrate
Chemical Properties
Molecular Weight238.24
FormulaC10H13NO4·3/2H2O
Cas No.41372-08-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 12 mg/mL (50.37 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1974 mL20.9872 mL41.9745 mL209.8724 mL
5 mM0.8395 mL4.1974 mL8.3949 mL41.9745 mL
10 mM0.4197 mL2.0987 mL4.1974 mL20.9872 mL
20 mM0.2099 mL1.0494 mL2.0987 mL10.4936 mL
50 mM0.0839 mL0.4197 mL0.8395 mL4.1974 mL

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