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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
5 mg | $93 | In Stock | |
10 mg | $148 | In Stock | |
25 mg | $328 | In Stock | |
50 mg | $528 | In Stock | |
100 mg | $769 | In Stock | |
1 mL x 10 mM (in DMSO) | $98 | In Stock |
Description | Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM) |
In vivo | ABX464 represents a novel class of anti-HIV molecules with unique properties. ABX464 has a long lasting effect in humanized mice and neutralizes the expression of HIV-1 proviral genome of infected immune cells including reservoirs and it is therefore a promising drug toward a functional cure of HIV[1]. |
Alias | ABX-464, ABX464 |
Molecular Weight | 338.71 |
Formula | C16H10ClF3N2O |
Cas No. | 1258453-75-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (295.24 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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