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Phenylbiguanide
🥰Excellent
Catalog No. T7135Cas No. 102-02-3
Alias PBG, N-Phenylbiguanide, 1-Phenylbiguanide
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
Phenylbiguanide
🥰Excellent
Purity: 99.87%
Catalog No. T7135Alias PBG, N-Phenylbiguanide, 1-PhenylbiguanideCas No. 102-02-3
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mg | $33 | In Stock | |
| 500 mg | $53 | In Stock | |
| 1 g | $77 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
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CitedSelect Batch
Purity:99.87%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM) |
| Targets&IC50 | 5-HT3:3 μM (EC50) |
| In vivo | Phenylbiguanide (PBG) is a drug known to stimulate cardiopulmonary afferent C-fibres. PBG is injected into the right atrium of the heart in anaesthetised mice and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[1]. |
| Alias | PBG, N-Phenylbiguanide, 1-Phenylbiguanide |
| Molecular Weight | 177.21 |
| Formula | C8H11N5 |
| Cas No. | 102-02-3 |
| Smiles | N(C(NC(=N)N)=N)C1=CC=CC=C1 |
| Relative Density. | 1.2512 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 150 mg/mL (846.45 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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