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Quipazine dimaleate

🥰Excellent
Catalog No. T23212Cas No. 150323-78-7

Quipazine dimaleate is a selective 5-HT3 agonist.

Quipazine dimaleate

Quipazine dimaleate

🥰Excellent
Purity: 100%
Catalog No. T23212Cas No. 150323-78-7
Quipazine dimaleate is a selective 5-HT3 agonist.
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10 mg$30In Stock
25 mg$44In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Quipazine dimaleate is a selective 5-HT3 agonist.
In vivo
Quipazine dimaleate dose-dependently reduces aggressive dominance in testosterone propionate-dominant rats, as well as in naturally dominant rats. When the serotonergic antagonists pirenpirone or pizotyline are coadministered with Quipazine dimaleate to either group of dominant rats, they blocks the effect of Quipazine dimaleate in reducing dominance[1].
Chemical Properties
Molecular Weight445.42
FormulaC21H23N3O8
Cas No.150323-78-7
SmilesOC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CN(CCN1)c1ccc2ccccc2n1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 29.7 mg/mL (90.0 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.2451 mL11.2254 mL22.4507 mL112.2536 mL
5 mM0.4490 mL2.2451 mL4.4901 mL22.4507 mL
10 mM0.2245 mL1.1225 mL2.2451 mL11.2254 mL
20 mM0.1123 mL0.5613 mL1.1225 mL5.6127 mL
50 mM0.0449 mL0.2245 mL0.4490 mL2.2451 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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