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SCH-900271

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Catalog No. T34573Cas No. 915210-50-3
Alias SCH 900271

SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.

SCH-900271

SCH-900271

🥰Excellent
Purity: 99%
Catalog No. T34573Alias SCH 900271Cas No. 915210-50-3
SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.
Pack SizePriceAvailabilityQuantity
1 mg114 €In Stock
5 mg275 €In Stock
10 mg418 €In Stock
25 mg691 €In Stock
50 mg937 €In Stock
100 mg1.320 €In Stock
500 mg2.631 €In Stock
1 mL x 10 mM (in DMSO)262 €In Stock
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Purity:99%
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Product Introduction

Bioactivity
Description
SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.
In vivo
In mice, SCH900271 could lowered FFAs acutely in humans ; however, neither had the expected effects on serum lipids. Chronic FFA suppression was not sustainable via GPR109A agonism with SCH900271.[2]
AliasSCH 900271
Chemical Properties
Molecular Weight276.29
FormulaC14H16N2O4
Cas No.915210-50-3
SmilesC(CCC1(C)CC1)C=2C3=C(NC(=O)NC3=O)OC(=O)C2
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.4 mg/mL (15.93 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6194 mL18.0969 mL36.1939 mL180.9693 mL
5 mM0.7239 mL3.6194 mL7.2388 mL36.1939 mL
10 mM0.3619 mL1.8097 mL3.6194 mL18.0969 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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