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Solamargine

Solamargine
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Purity:99.76%
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Solamargine

Catalog No. T4034Cas No. 20311-51-7
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells.
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Pack SizePriceAvailabilityQuantity
1 mg$54In Stock
5 mg$117In Stock
10 mg$177In Stock
25 mg$363In Stock
50 mg$562In Stock
100 mg$790In Stock
1 mL x 10 mM (in DMSO)$169In Stock
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Product Introduction

Bioactivity
Description
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells.
In vitro
Solamargine concentration-dependently reduced HepG2 cell viability. Solamargine (7.5 μM) reduced cell viability by less than 20% in HepG2 cells. Solamargine (highest dose) decreased cell invasion and migration by more than 72% and 70% in HepG2 cells, respectively. Solamargine reduced function and expression of MMP-2/9 proteins. Solamargine time-dependently increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) in a fashion.
AliasSolamargin, δ-Solanigrine
Chemical Properties
Molecular Weight868.06
FormulaC45H73NO15
Cas No.20311-51-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 91 mg/mL(104.8 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1520 mL5.7600 mL11.5199 mL57.5997 mL
5 mM0.2304 mL1.1520 mL2.3040 mL11.5199 mL
10 mM0.1152 mL0.5760 mL1.1520 mL5.7600 mL
20 mM0.0576 mL0.2880 mL0.5760 mL2.8800 mL
50 mM0.0230 mL0.1152 mL0.2304 mL1.1520 mL
100 mM0.0115 mL0.0576 mL0.1152 mL0.5760 mL

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