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Sulfamerazine

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Purity:99.77%

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COA HNMR LCMS HPLC

Sulfamerazine

Catalog No. T0913Cas No. 127-79-7

Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.

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Pack Size	Price	Availability
200 mg	$37	In Stock
500 mg	$58	In Stock
1 g	$97	In Stock
5 g	$394	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Product Introduction

Bioactivity

Description	Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
In vitro	Sulfamerazine significantly affects the lifespan of rats, markedly prolonging the life of male hamsters. The maximum body weight of all rats fed with sulfamerazine exceeded that of the control group. After oral administration of sulfamerazine, significant alterations in the shape of the concentration-time curve due to age were observed, strongly indicating absorption deficiencies within the first week after birth in lambs.
In vivo	Sulfamerazine exhibits a bi-exponential decay in water and a tri-exponential decay in cyclodextrin (CD) solutions. The resonance of aromatic protons in Sulfamerazine indicates a significant upfield shift, suggesting that the aniline ring is deeply encapsulated within the CD cavity.
Alias	RP2632

Chemical Properties

Molecular Weight	264.3
Formula	C11H12N4O2S
Cas No.	127-79-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (227.01 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7836 mL	18.9179 mL	37.8358 mL	189.1790 mL
5 mM	0.7567 mL	3.7836 mL	7.5672 mL	37.8358 mL
10 mM	0.3784 mL	1.8918 mL	3.7836 mL	18.9179 mL
20 mM	0.1892 mL	0.9459 mL	1.8918 mL	9.4589 mL
50 mM	0.0757 mL	0.3784 mL	0.7567 mL	3.7836 mL
100 mM	0.0378 mL	0.1892 mL	0.3784 mL	1.8918 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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