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Sulfamerazine

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Catalog No. T0913Cas No. 127-79-7
Alias RP2632

Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.

Sulfamerazine

Sulfamerazine

🥰Excellent
Purity: 99.77%
Catalog No. T0913Alias RP2632Cas No. 127-79-7
Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
Pack SizePriceAvailabilityQuantity
200 mg$37In Stock
500 mg$58In Stock
1 g$97In Stock
5 g$394In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.77%
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Product Introduction

Bioactivity
Description
Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
In vitro
Sulfamerazine significantly affects the lifespan of rats, markedly prolonging the life of male hamsters. The maximum body weight of all rats fed with sulfamerazine exceeded that of the control group. After oral administration of sulfamerazine, significant alterations in the shape of the concentration-time curve due to age were observed, strongly indicating absorption deficiencies within the first week after birth in lambs.
In vivo
Sulfamerazine exhibits a bi-exponential decay in water and a tri-exponential decay in cyclodextrin (CD) solutions. The resonance of aromatic protons in Sulfamerazine indicates a significant upfield shift, suggesting that the aniline ring is deeply encapsulated within the CD cavity.
AliasRP2632
Chemical Properties
Molecular Weight264.3
FormulaC11H12N4O2S
Cas No.127-79-7
SmilesCC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1
Relative Density.1.439 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (227.01 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7836 mL18.9179 mL37.8358 mL189.1790 mL
5 mM0.7567 mL3.7836 mL7.5672 mL37.8358 mL
10 mM0.3784 mL1.8918 mL3.7836 mL18.9179 mL
20 mM0.1892 mL0.9459 mL1.8918 mL9.4589 mL
50 mM0.0757 mL0.3784 mL0.7567 mL3.7836 mL
100 mM0.0378 mL0.1892 mL0.3784 mL1.8918 mL

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