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Tetrahydroberberine

🥰Excellent
Catalog No. T2874Cas No. 522-97-4
Alias Tetrahydroberberine THB, Canadine

Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.

Tetrahydroberberine

Tetrahydroberberine

🥰Excellent
Purity: 99.89%
Catalog No. T2874Alias Tetrahydroberberine THB, CanadineCas No. 522-97-4
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$57In Stock
25 mg$94In Stock
50 mg$139In Stock
100 mg$198In Stock
500 mg$513In Stock
1 mL x 10 mM (in DMSO)$52In Stock
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Purity:99.89%
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Product Introduction

Bioactivity
Description
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
Targets&IC50
D2 receptor:6.08(pKi), 5-HT1A:5.38(pKi)
AliasTetrahydroberberine THB, Canadine
Chemical Properties
Molecular Weight339.39
FormulaC20H21NO4
Cas No.522-97-4
SmilesCOC1=C(OC)C2=C(CC3N(CCC4=CC5=C(OCO5)C=C34)C2)C=C1
Relative Density.1.33 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3.73 mg/mL (10.99 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9465 mL14.7323 mL29.4646 mL147.3231 mL
5 mM0.5893 mL2.9465 mL5.8929 mL29.4646 mL
10 mM0.2946 mL1.4732 mL2.9465 mL14.7323 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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