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Toyocamycin
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Toyocamycin
Catalog No. T17143Cas No. 606-58-6
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $39 | In Stock | |
| 10 mg | $59 | In Stock | |
| 25 mg | $115 | In Stock | |
| 50 mg | $213 | In Stock | |
| 100 mg | $372 | In Stock | |
| 500 mg | $869 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $43 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. |
| Alias | Vengicide |
| Molecular Weight | 291.26 |
| Formula | C12H13N5O4 |
| Cas No. | 606-58-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (343.34 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Keywords
RNA synthesisCDKmRNA cleavageepigeneticsIRE1CDK9 inhibitorCyclin dependent kinasemolecular dockingreactive oxygen speciesCDKsRNA Pol II phosphorylationInositol requiring enzyme 1FungalInhibitoradenosine analogAntibioticToyocamycindrug screeningribosome functioninhibitApoptosisextracellular signal-regulated kinasescancer
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