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Toyocamycin

🥰Excellent
Catalog No. T17143Cas No. 606-58-6
Alias Vengicide

Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.

Toyocamycin

Toyocamycin

🥰Excellent
Purity: 98.17%
Catalog No. T17143Alias VengicideCas No. 606-58-6
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.
Pack SizePriceAvailabilityQuantity
5 mg37 €In Stock
10 mg56 €In Stock
25 mg109 €In Stock
50 mg202 €In Stock
100 mg353 €In Stock
500 mg825 €In Stock
1 mL x 10 mM (in DMSO)40 €In Stock
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Purity:98.17%
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Product Introduction

Bioactivity
Description
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.
Targets&IC50
XBP1:80 nM
AliasVengicide
Chemical Properties
Molecular Weight291.26
FormulaC12H13N5O4
Cas No.606-58-6
SmilesNc1ncnc2n(cc(C#N)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Relative Density.1.91g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (343.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4334 mL17.1668 mL34.3336 mL171.6679 mL
5 mM0.6867 mL3.4334 mL6.8667 mL34.3336 mL
10 mM0.3433 mL1.7167 mL3.4334 mL17.1668 mL
20 mM0.1717 mL0.8583 mL1.7167 mL8.5834 mL
50 mM0.0687 mL0.3433 mL0.6867 mL3.4334 mL
100 mM0.0343 mL0.1717 mL0.3433 mL1.7167 mL

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