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Vicriviroc maleate

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Catalog No. T3435Cas No. 599179-03-0
Alias SCH-D (maleate), SCH-417690 (maleate)

Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.

Vicriviroc maleate

Vicriviroc maleate

🥰Excellent
Purity: 98.16%
Catalog No. T3435Alias SCH-D (maleate), SCH-417690 (maleate)Cas No. 599179-03-0
Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.
Pack SizePriceAvailabilityQuantity
1 mg$35In Stock
5 mg$86In Stock
10 mg$133In Stock
25 mg$236In Stock
50 mg$356In Stock
100 mg$535In Stock
1 mL x 10 mM (in DMSO)$119In Stock
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Purity:98.16%
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Product Introduction

Bioactivity
Description
Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.
Targets&IC50
CCR5 receptor:0.91 nM
AliasSCH-D (maleate), SCH-417690 (maleate)
Chemical Properties
Molecular Weight649.7
FormulaC32H42F3N5O6
Cas No.599179-03-0
SmilesOC(=O)\C=C/C(O)=O.COC[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(cc1)C(F)(F)F
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (76.96 mM), Sonication is recommended.
H2O: 25 mg/mL (38.48 mM), Sonication and heating are recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.5392 mL7.6959 mL15.3917 mL76.9586 mL
5 mM0.3078 mL1.5392 mL3.0783 mL15.3917 mL
10 mM0.1539 mL0.7696 mL1.5392 mL7.6959 mL
20 mM0.0770 mL0.3848 mL0.7696 mL3.8479 mL
DMSO
1mg5mg10mg50mg
50 mM0.0308 mL0.1539 mL0.3078 mL1.5392 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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