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Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $35 | In Stock | |
5 mg | $86 | In Stock | |
10 mg | $133 | In Stock | |
25 mg | $236 | In Stock | |
50 mg | $356 | In Stock | |
100 mg | $535 | In Stock | |
1 mL x 10 mM (in DMSO) | $119 | In Stock |
Description | Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1. |
Targets&IC50 | CCR5 receptor:0.91 nM |
Alias | SCH-D (maleate), SCH-417690 (maleate) |
Molecular Weight | 649.7 |
Formula | C32H42F3N5O6 |
Cas No. | 599179-03-0 |
Smiles | OC(=O)\C=C/C(O)=O.COC[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(cc1)C(F)(F)F |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (76.96 mM), Sonication is recommended. H2O: 25 mg/mL (38.48 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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