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VU 0365114

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Catalog No. T13325Cas No. 1208222-39-2

VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).

VU 0365114

VU 0365114

🥰Excellent
Purity: 97.29%
Catalog No. T13325Cas No. 1208222-39-2
VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).
Pack SizePriceAvailabilityQuantity
2 mg$32In Stock
5 mg$53In Stock
10 mg$75In Stock
25 mg$139In Stock
50 mg$235In Stock
100 mg$353In Stock
200 mg$493In Stock
1 mL x 10 mM (in DMSO)$59In Stock
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Purity:97.29%
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Product Introduction

Bioactivity
Description
VU 0365114 is a positive allosteric modulator of mAChR M5 (EC50: 2.7 μM).
Targets&IC50
M5 mAChR:2.7 μM(EC50)
Chemical Properties
Molecular Weight397.35
FormulaC22H14F3NO3
Cas No.1208222-39-2
SmilesFC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
Relative Density.1.386 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMSO: 45 mg/mL (113.25 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5167 mL12.5834 mL25.1667 mL125.8336 mL
5 mM0.5033 mL2.5167 mL5.0333 mL25.1667 mL
10 mM0.2517 mL1.2583 mL2.5167 mL12.5834 mL
20 mM0.1258 mL0.6292 mL1.2583 mL6.2917 mL
50 mM0.0503 mL0.2517 mL0.5033 mL2.5167 mL
100 mM0.0252 mL0.1258 mL0.2517 mL1.2583 mL

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