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VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $30 | In Stock | |
25 mg | $53 | In Stock | |
50 mg | $80 | In Stock | |
100 mg | $119 | In Stock | |
200 mg | $178 | In Stock | |
1 mL x 10 mM (in DMSO) | $33 | In Stock |
Description | VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent. |
Targets&IC50 | M1:3.1 μM(EC50) |
In vivo | VU0119498 treatment of wild-type mice caused a significant increase in plasma insulin levels, accompanied by a striking improvement in glucose tolerance |
Molecular Weight | 316.15 |
Formula | C15H10BrNO2 |
Cas No. | 79183-37-2 |
Smiles | Brc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1 |
Relative Density. | 1.604 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (47.45 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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