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NGB 2904

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Purity:99.35%

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COA HPLC HNMR

NGB 2904

Catalog No. T28167Cas No. 189060-98-8

NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).

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Pack Size	Price	Availability
2 mg	$34	In Stock
5 mg	$53	In Stock
10 mg	$83	In Stock
25 mg	$166	In Stock
50 mg	$294	In Stock
100 mg	$415	In Stock
500 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$69	In Stock

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Product Introduction

Bioactivity

Description	NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
Alias	NGB2904 HCl, NGB-2904, NGB2904

Chemical Properties

Molecular Weight	494.46
Formula	C28H29Cl2N3O
Cas No.	189060-98-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 16.25 mg/ml (30.61 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0224 mL	10.1120 mL	20.2241 mL	101.1204 mL
5 mM	0.4045 mL	2.0224 mL	4.0448 mL	20.2241 mL
10 mM	0.2022 mL	1.0112 mL	2.0224 mL	10.1120 mL
20 mM	0.1011 mL	0.5056 mL	1.0112 mL	5.0560 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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