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4-MMPB
🥰Excellent
Catalog No. T8794Cas No. 928853-86-5
Alias 15-Lipoxygenase Inhibitor 1
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.
4-MMPB
🥰Excellent
Purity: 97.18%
Catalog No. T8794Alias 15-Lipoxygenase Inhibitor 1Cas No. 928853-86-5
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $37 | In Stock | |
| 5 mg | $85 | In Stock | |
| 10 mg | $139 | In Stock | |
| 25 mg | $278 | In Stock | |
| 50 mg | $455 | In Stock | |
| 100 mg | $745 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $94 | In Stock |
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Purity:97.18%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer. |
| Targets&IC50 | Others:69.6 μM |
| In vitro | 15-Lipoxygenase Inhibitor 1 has an IC50 of 69.6 μM for DPPH bleaching；15-Lipoxygenase Inhibitor 1 (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells[1][2]. |
| Alias | 15-Lipoxygenase Inhibitor 1 |
| Molecular Weight | 313.42 |
| Formula | C16H19N5S |
| Cas No. | 928853-86-5 |
| Smiles | CN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1 |
| Relative Density. | 1.265 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 8 mg/mL (25.52 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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