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Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 g | $50 | In Stock | |
10 g | $65 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor. |
Targets&IC50 | XO:7.82±0.12 μM |
In vitro | 10 mM Allopurinol inhibited the activity of oxygen xanthine oxidase produced by hypoxia-reoxygenation injury.Allopurinol reduced intracellular Ca2+ concentration by enhancing xanthine oxidase activity.Allopurinol reversed the increase in xanthine oxidase activity in neonatal rat hearts with ischemia-reperfusion injury. |
In vivo | 10 mM Allopurinol inhibited the activity of oxygen xanthine oxidase produced by hypoxia-reoxygenation injury.Allopurinol reduced intracellular Ca2+ concentration by enhancing xanthine oxidase activity.Allopurinol reversed the increase in xanthine oxidase activity in neonatal rat hearts with ischemia-reperfusion injury. |
Alias | Zyloric, Zyloprim, Lopurin |
Molecular Weight | 136.11 |
Formula | C5H4N4O |
Cas No. | 315-30-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 3 mg/mL (22.04 mM) H2O: Insoluble DMSO: 15 mg/mL (110.2 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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