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Febuxostat

Catalog No. T0773   CAS 144060-53-7
Synonyms: TMX 67, TEI 6720

Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.

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Febuxostat Chemical Structure
Febuxostat, CAS 144060-53-7
Pack Size Availability Price/USD Quantity
5 mg In stock $ 32.00
10 mg In stock $ 52.00
25 mg In stock $ 80.00
50 mg In stock $ 107.00
100 mg In stock $ 135.00
200 mg In stock $ 198.00
500 mg In stock $ 338.00
1 mL * 10 mM (in DMSO) In stock $ 54.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.
Targets&IC50 XO:0.6 nM(Ki)
Synonyms TMX 67, TEI 6720
Molecular Weight 316.37
Formula C16H16N2O3S
CAS No. 144060-53-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 23.7 mg/mL (75 mM)

Ethanol: 15.8 mg/mL (50 mM)

TargetMolReferences and Literature

1. Takano Y, et al. Life Sci, 2005, 76(16), 1835-1847. 2. Sánchez-Lozada LG, et al. Am J Physiol Renal Physiol. 2008 Apr;294(4):F710-8. 3. Sánchez-Lozada LG, et al. Nephron Physiol. 2008;108(4):p69-78. 4. Xu X, et al. Card Fail, 2008, 14(9), 746-753. 5. Tsuda H, et al. Biochem Biophys Res Commun, 2012, 427(2), 266-272. 6. Wang F, Ye W, Wang S, et al. D. Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy[J]. Neoplasia. 2021, 23(3): 281-293.

TargetMolCitations

1. Wang F, Ye W, Wang S, et al. D Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy. Neoplasia. 2021, 23(3): 281-293.

Related compound libraries

This product is contained In the following compound libraries:
FDA-Approved Kinase Inhibitor Library FDA-Approved Drug Library Kinase Inhibitor Library Ferroptosis Compound Library Anti-Obesity Compound Library Anti-Fibrosis Compound Library Approved Drug Library Drug-induced Liver Injury (DILI) Compound Library Metabolism Compound Library Orally Active Compound Library

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Febuxostat 144060-53-7 Immunology/Inflammation Metabolism ROS Xanthine Oxidase metabolic syndrome Inhibitor p-mTOR Hyperuricemia TEI6720 TMX 67 gout TMX-67 TEI-6720 TMX67 inhibit TEI 6720 p-Erk inhibitor

 

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