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Nicotinamide riboside

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Catalog No. T13795Cas No. 1341-23-7

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

Nicotinamide riboside

Nicotinamide riboside

🥰Excellent
Purity: 99.58%
Catalog No. T13795Cas No. 1341-23-7
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
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5 mg$50In Stock
200 mg$240In Stock
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Purity:99.58%
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Product Introduction

Bioactivity
Description
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
In vitro
Nicotinamide riboside (NR) supplementation in mammalian cells and mouse tissues increases NAD(+) levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities.
In vivo
The natural vitamin Nicotinamide riboside (NR) could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function.
Chemical Properties
Molecular Weight255.25
FormulaC11H15N2O5
Cas No.1341-23-7
SmilesO[C@H]1[C@@H](O[C@H](CO)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2
Relative Density.1.201g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (195.89 mM)
H2O: 50 mg/mL (195.89 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.9177 mL19.5886 mL39.1773 mL195.8864 mL
5 mM0.7835 mL3.9177 mL7.8355 mL39.1773 mL
10 mM0.3918 mL1.9589 mL3.9177 mL19.5886 mL
20 mM0.1959 mL0.9794 mL1.9589 mL9.7943 mL
50 mM0.0784 mL0.3918 mL0.7835 mL3.9177 mL
100 mM0.0392 mL0.1959 mL0.3918 mL1.9589 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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