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Nicotinamide riboside

Catalog No. T13795 CAS 1341-23-7

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

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Nicotinamide riboside Chemical Structure

Nicotinamide riboside, CAS 1341-23-7

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5 mg	In stock	$ 50.00
200 mg	In stock	$ 240.00

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Purity: 99.58%

Purity: 98.61%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
In vitro	Nicotinamide riboside (NR) supplementation in mammalian cells and mouse tissues increases NAD(+) levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities.
In vivo	The natural vitamin Nicotinamide riboside (NR) could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function.

Molecular Weight	255.25
Formula	C11H15N2O5
CAS No.	1341-23-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

H2O: 50 mg/mL (195.89 mM), Sonification is recommended.

References and Literature

1. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.

Citations

1. Zhao S, Hong Y, Liang Y, et al. Compartmentalized regulation of NAD+ by Di (2-ethyl-hexyl) phthalate induces DNA damage in placental trophoblast. Redox biology. 2022, 55: 102414.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Epigenetics Compound Library Human Metabolite Library Histone Modification Compound Library Clinical Compound Library DNA Damage & Repair Compound Library Human Endogenous Metabolite Compound Library Plus Bioactive Compounds Library Max ReFRAME Related Library Anti-Diabetic Compound Library

Related Products

Related compounds with same targets

Ginkgolide C Scopolin UBCS039 SIRT5 inhibitor 6 3-TYP Sirtinol JGB1741 5-Feruloylquinic acid

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Keywords

Nicotinamide riboside 1341-23-7 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin Endogenous Metabolite niacin metabolic dietary orally Inhibitor vitamin oxidative supplements PARP abnormalities COVID-19 metabolism inhibit NAD+ Alzheimer’s inhibitor

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