Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 46.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 422.00 | |
100 mg | In stock | $ 678.00 |
Description | Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. |
In vitro | Sugammadex has a high affinity for Pipecuronium bromide. As Pipecuronium bromide is approximately 6 to 7 times more potent than Rocuronium, Sugammadex achieves a more effective molecular blockade compared to Rocuronium [3]. |
In vivo | Sugammadex adequately and rapidly reverses pipecuronium bromide induced moderate NMB during sevoflurane anesthesia. Once the train-of-four count has spontaneously returned to 2 responses following pipecuronium bromide administration, a dose of 2.0 mg/kg of sugammadex is sufficient to reverse the NMB[2].Carboxymethylated γ-cyclodextrin demonstrates efficient and complete reversal of the Pipecuronium bromide-induced neuromuscular block in an ex vivo rat diaphragm experiment [1]. |
Synonyms | RGH-1106 |
Molecular Weight | 762.7 |
Formula | C35H62Br2N4O4 |
CAS No. | 52212-02-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 80 mg/mL (104.89 mM), Sonication is recommended.
DMSO: 120 mg/mL (157.34 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Pipecuronium bromide 52212-02-9 Neuroscience AChR RGH-1106 inhibitor inhibit