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Primidone

Catalog No. T0024 CAS 125-33-7

Synonyms: NCI-C56360, Primaclone, Mysoline

Primidone is an anticonvulsant of the pyrimidinedione class.

Primidone, CAS 125-33-7

Pack Size	Availability	Price/USD
50 mg	In stock	60.00
100 mg	In stock	75.00
200 mg	In stock	130.00
1 mL * 10 mM (in DMSO)	In stock	50.00

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Purity 99.66%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Primidone is an anticonvulsant of the pyrimidinedione class.
Targets&IC50	GABAR, GluR2, nAChR, Sodium Channel,

Synonyms	NCI-C56360 , Primaclone , Mysoline
Purity	99.66%
Molecular Weight	218.26
Formula	C12H14N2O2
CAS No.	125-33-7

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 21.8 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Yamakura T, et al. Annu Rev Pharmacol Toxicol. 2001;41:23-51.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Neuronal Signaling Compound Library Ion Channel Inhibitor Library FDA-approved Drug Library Anti-Cardiovascular Disease Compound Library CNS-Penetrant Compound Library

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.