Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 70.00 | |
5 mg | In stock | $ 117.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 513.00 | |
100 mg | In stock | $ 748.00 | |
500 mg | In stock | $ 1,560.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 129.00 |
Description | RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity |
In vitro | RRx-001 inhibited the growth of colon cancer cells (HCT 116) and decreased levels of the DNA methyltransferases DNMT1 and DNMT3a in a time and dose-dependent manner. Treatment of HCT 116 cells with 0.5 μM RRx-001 for 24 h significantly increased transcripts of interferon (IFN)-responsive genes and this induction was sustained for up to 4 weeks after transient exposure to RRx-001. RRx-001 increased secretion of type I and III IFNs by HCT 116 cells, and these IFNs were confirmed to be bioactive. Transcription of endogenous retrovirus ERV-Fc2 and LTRs from the ERV-L family (MLT2B4 and MLT1C49) was induced by RRx-001[1]. |
Molecular Weight | 268.02 |
Formula | C5H6BrN3O5 |
CAS No. | 925206-65-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (373.11 mM)
You can also refer to dose conversion for different animals. More
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RRX-001 925206-65-1 Apoptosis Metabolism Microbiology/Virology Dehydrogenase Parasite RRX 001 RRx-001 Inhibitor RRX001 inhibit inhibitor