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Rhosin hydrochloride
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Rhosin hydrochloride
Catalog No. T16745Cas No. 1281870-42-5
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $162 | In Stock | |
| 2 mg | $229 | In Stock | |
| 5 mg | $347 | In Stock | |
| 10 mg | $497 | In Stock | |
| 25 mg | $793 | In Stock | |
| 50 mg | $1,080 | In Stock | |
| 100 mg | $1,450 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $382 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin h |
| In vitro | Rhosin hydrochloride causes decreased size and reduced number of mammospheres in MCF7 cells. Rhosin hydrochloride dose-dependently reduces RhoA and p-MLC1 activities of MCF7 cell-derived mammospheres (EC50: ~30-50 μM) [1]. |
| Molecular Weight | 431.318 |
| Formula | C20H20Cl2N6O |
| Cas No. | 1281870-42-5 |
| Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (253.25 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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