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Rotundine

Catalog No. T6648Cas No. 483-14-7
Alias L-Tetrahydropalmatine, Gindarine, Caseanine, (-)-Tetrahydropalmatine

Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

Rotundine

Rotundine

Purity: 100%
Catalog No. T6648Alias L-Tetrahydropalmatine, Gindarine, Caseanine, (-)-TetrahydropalmatineCas No. 483-14-7
Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
Pack SizePriceAvailabilityQuantity
50 mg$31In Stock
100 mg$44In Stock
500 mg$98In Stock
1 g$148In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
Targets&IC50
D1 receptor:166 nM
In vitro
Cidofovir inhibits human cytomegalovirus (HCMV) infection in cultured cells. Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. [1] Cidofovir also inhibits herpes simplex virus infection. In addition, Cidofovir blocks cell fusion induced by HSV-1 in monkey kidney cells and blocks the expression of HSV-l-specific proteins and the synthesis of viral DNA. [3]
AliasL-Tetrahydropalmatine, Gindarine, Caseanine, (-)-Tetrahydropalmatine
Chemical Properties
Molecular Weight355.43
FormulaC21H25NO4
Cas No.483-14-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (154.74 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8135 mL14.0675 mL28.1349 mL140.6747 mL
5 mM0.5627 mL2.8135 mL5.6270 mL28.1349 mL
10 mM0.2813 mL1.4067 mL2.8135 mL14.0675 mL
20 mM0.1407 mL0.7034 mL1.4067 mL7.0337 mL
50 mM0.0563 mL0.2813 mL0.5627 mL2.8135 mL
100 mM0.0281 mL0.1407 mL0.2813 mL1.4067 mL

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