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Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
2 mg | $54 | In Stock | |
5 mg | $82 | In Stock | |
10 mg | $143 | In Stock | |
25 mg | $248 | In Stock | |
50 mg | $389 | In Stock | |
100 mg | $569 | In Stock | |
500 mg | $1,190 | In Stock |
Description | Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome. |
In vitro | Tedizolid (0.25 μg/mL) effectively inhibits all 28 clinical isolates of PRSP, demonstrating a potency four times greater than linezolid against PRSP[1]. |
In vivo | The tedizolid phosphate at a minimum total daily dose of 10 mg/kg achieved a 100% survival rate for mice infected with PSSP type III. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema[1]. |
Alias | TR 700, Torezolid, DA-7157 |
Molecular Weight | 370.34 |
Formula | C17H15FN6O3 |
Cas No. | 856866-72-3 |
Smiles | O=C1N(C[C@H](CO)O1)C2=CC(F)=C(C=C2)C=3C=CC(=NC3)C4=NN(C)N=N4 |
Relative Density. | 1.57 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | DMSO: 2.8 mg/mL (7.56 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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