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Tetramethylcurcumin

Catalog No. TN2269Cas No. 52328-97-9

Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.

Tetramethylcurcumin

Tetramethylcurcumin

Purity: 99.94%
Catalog No. TN2269Cas No. 52328-97-9
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$89In Stock
10 mg$143In Stock
25 mg$289In Stock
50 mg$428In Stock
100 mg$623In Stock
1 mL x 10 mM (in DMSO)$109In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.
Chemical Properties
Molecular Weight424.49
FormulaC25H28O6
Cas No.52328-97-9
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (58.89 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3558 mL11.7788 mL23.5577 mL117.7884 mL
5 mM0.4712 mL2.3558 mL4.7115 mL23.5577 mL
10 mM0.2356 mL1.1779 mL2.3558 mL11.7788 mL
20 mM0.1178 mL0.5889 mL1.1779 mL5.8894 mL
50 mM0.0471 mL0.2356 mL0.4712 mL2.3558 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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