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AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $46 | In Stock | |
2 mg | $59 | In Stock | |
5 mg | $77 | In Stock | |
10 mg | $126 | In Stock | |
25 mg | $239 | In Stock | |
50 mg | $369 | In Stock | |
100 mg | $549 | In Stock | |
500 mg | $1,190 | In Stock | |
1 mL x 10 mM (in DMSO) | $80 | In Stock |
Description | AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM). |
Targets&IC50 | CXCR2:0.79 nM |
In vitro | AZD5069 inhibited neutrophil chemotaxis, with a pA2 of approximately 9.6, and adhesion molecule expression, with a pA2 of 6.9, in response to CXCL1[1] |
Molecular Weight | 476.52 |
Formula | C18H22F2N4O5S2 |
Cas No. | 878385-84-3 |
Smiles | C[C@@H](Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)[C@@H](O)CO |
Relative Density. | 1.56 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (188.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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