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Benzethonium chloride
🥰Excellent
Catalog No. T0401Cas No. 121-54-0
Alias Quatrachlor, Phemeride, Hyamine
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
Benzethonium chloride
🥰Excellent
Purity: 97.5%
Catalog No. T0401Alias Quatrachlor, Phemeride, HyamineCas No. 121-54-0
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | 34 € | In Stock | |
| 100 mg | 48 € | In Stock | |
| 200 mg | 64 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 47 € | In Stock |
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Purity:97.5%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. |
| Targets&IC50 | α7 nAChR:122 nM, α4β2 nAChR:49 nM |
| In vitro | Administered in SCID mice bearing human laryngeal squamous cell carcinoma tumors, Benzethonium chloride (5 mg/kg) inhibited the growth of xenografts. |
| In vivo | In human hypopharyngeal squamous carcinoma cells, Benzethonium chloride at a concentration of 9 µM induces apoptosis and activates caspases after 12 hours. Furthermore, Benzethonium chloride at 5 µM enhances the effect of glucose consumption on the intracellular solute Ca(2+) concentration and its binding to membrane-associated proteins. |
| Cell Research | Cells are seeded in 96-well plates at 5,000 per well in 100 μL of growth medium and allowed to incubate for 24 hours. Benzethonium chloride is then added, as indicated, in a total volume of 5 μL. After 48 hours, MTS assay is done according to the specifications of the manufacturer, with DMSO (0.1%)–treated cells as negative control and cisplatin (166.6 μM)–treated cells as positive control.(Only for Reference) |
| Alias | Quatrachlor, Phemeride, Hyamine |
| Molecular Weight | 448.09 |
| Formula | C27H42ClNO2 |
| Cas No. | 121-54-0 |
| Smiles | [Cl-].CC(C)(C)CC(C)(C)C1=CC=C(OCCOCC[N+](C)(C)CC2=CC=CC=C2)C=C1 |
| Relative Density. | 1.1. Temperature:20 °C. |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (100.43 mM)  H2O: 83 mg/mL (185.2 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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