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Benzethonium chloride

Benzethonium chloride
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
Catalog No. T0401Cas No. 121-54-0
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Purity:97.5%
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Benzethonium chloride

Catalog No. T0401Cas No. 121-54-0

Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
50 mg$36In Stock
100 mg$51In Stock
200 mg$68In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
Targets&IC50
α7 nAChR:122 nM, α4β2 nAChR:49 nM
In vitro
Administered in SCID mice bearing human laryngeal squamous cell carcinoma tumors, Benzethonium chloride (5 mg/kg) inhibited the growth of xenografts.
In vivo
In human hypopharyngeal squamous carcinoma cells, Benzethonium chloride at a concentration of 9 µM induces apoptosis and activates caspases after 12 hours. Furthermore, Benzethonium chloride at 5 µM enhances the effect of glucose consumption on the intracellular solute Ca(2+) concentration and its binding to membrane-associated proteins.
Cell Research
Cells are seeded in 96-well plates at 5,000 per well in 100 μL of growth medium and allowed to incubate for 24 hours. Benzethonium chloride is then added, as indicated, in a total volume of 5 μL. After 48 hours, MTS assay is done according to the specifications of the manufacturer, with DMSO (0.1%)–treated cells as negative control and cisplatin (166.6 μM)–treated cells as positive control.(Only for Reference)
AliasHyamine, Phemeride, Quatrachlor
Chemical Properties
Molecular Weight448.09
FormulaC27H42ClNO2
Cas No.121-54-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (100.43 mM)
H2O: 83 mg/mL (185.2 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.2317 mL11.1585 mL22.3169 mL111.5847 mL
5 mM0.4463 mL2.2317 mL4.4634 mL22.3169 mL
10 mM0.2232 mL1.1158 mL2.2317 mL11.1585 mL
20 mM0.1116 mL0.5579 mL1.1158 mL5.5792 mL
50 mM0.0446 mL0.2232 mL0.4463 mL2.2317 mL
100 mM0.0223 mL0.1116 mL0.2232 mL1.1158 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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