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Clorsulon

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Purity:99.44%

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COA HNMR LCMS

Clorsulon

Catalog No. T1137Cas No. 60200-06-8

Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.

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Pack Size	Price	Availability
50 mg	$42	In Stock
100 mg	$59	In Stock
200 mg	$92	In Stock
500 mg	$158	In Stock
1 mL x 10 mM (in DMSO)	$65	In Stock

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Product Introduction

Bioactivity

Description	Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
In vitro	In sheep and calves, a single administration of Clorsulon (15 mg/kg) effectively induces damage to the cortical and intestinal tissues of the liver flukes, thereby expelling immature liver flukes from the host organism.
In vivo	Clorsulon is a competitive inhibitor (Ki=0.29 mM) of both 3-phosphoglycerate and ATP, capable of suppressing glucose utilization and the formation of acetate and propionate.
Alias	L631529, MK401

Chemical Properties

Molecular Weight	380.66
Formula	C8H8Cl3N3O4S2
Cas No.	60200-06-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 7 mg/mL (18.38 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 71 mg/mL (186.5 mM)

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.6270 mL	13.1351 mL	26.2702 mL	131.3508 mL
5 mM	0.5254 mL	2.6270 mL	5.2540 mL	26.2702 mL
10 mM	0.2627 mL	1.3135 mL	2.6270 mL	13.1351 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1314 mL	0.6568 mL	1.3135 mL	6.5675 mL
50 mM	0.0525 mL	0.2627 mL	0.5254 mL	2.6270 mL
100 mM	0.0263 mL	0.1314 mL	0.2627 mL	1.3135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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