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F-15599
🥰Excellent
Catalog No. T7281Cas No. 635323-95-4
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist (Ki: 3.4 nM).
F-15599
🥰Excellent
Purity: 98.72%
Catalog No. T7281Cas No. 635323-95-4
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist (Ki: 3.4 nM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $44 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $163 | In Stock | |
| 25 mg | $328 | In Stock | |
| 50 mg | $529 | In Stock | |
| 100 mg | $795 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $137 | In Stock |
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CitedSelect Batch
Purity:98.72%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist (Ki: 3.4 nM). |
| Targets&IC50 | 5-HT1A:3.4 nM(ki) |
| In vivo | F-15599 exerted very potent (ID50 = 0.095 and 0.0059 mg/kg, respectively) anti-aggressive effects in male WTG rats. At 4.5-fold higher dose ranges, the anti-aggressive effects were accompanied by concomitant motor inactivity and/or reduction of social engagement. Pretreatment with WAY-100635 counteracted the behavioural effects of both agonists[1]. |
| Animal Research | F-15599 agonists were acutely administered intraperitoneally in aggressive resident male WTG rats confronting an intruder[1]. |
| Molecular Weight | 394.85 |
| Formula | C19H21ClF2N4O |
| Cas No. | 635323-95-4 |
| Smiles | Cc1cnc(CNCC2(F)CCN(CC2)C(=O)c2ccc(F)c(Cl)c2)nc1 |
| Relative Density. | 1.33 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (56.98 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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