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Lotilaner

Lotilaner
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Purity:99.32%
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Lotilaner

Catalog No. T15775Cas No. 1369852-71-0
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
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Pack SizePriceAvailabilityQuantity
1 mg$84In Stock
2 mg$122In Stock
5 mg$198In Stock
10 mg$328In Stock
25 mg$622In Stock
50 mg$955In Stock
100 mg$1,390In Stock
200 mg$1,880In Stock
500 mg$2,830In Stock
1 mL x 10 mM (in DMSO)$268In Stock
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Product Introduction

Bioactivity
Description
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
In vitro
Lotilaner displays IC50s of 38.25 ± 3.75, 52.40 ± 4.54, 36.79 ± 4.39 nM for Drosophila melanogaster dieldrin/fipronil-resistant forms (DmR2), Lepeophtheirus salmonis (Ls) and Rhipicephalus microplus (Rm) GABACl receptors, respectively.
Chemical Properties
Molecular Weight596.76
FormulaC20H14Cl3F6N3O3S
Cas No.1369852-71-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: ≥ 150 mg/mL (251.36 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6757 mL8.3786 mL16.7572 mL83.7858 mL
5 mM0.3351 mL1.6757 mL3.3514 mL16.7572 mL
10 mM0.1676 mL0.8379 mL1.6757 mL8.3786 mL
20 mM0.0838 mL0.4189 mL0.8379 mL4.1893 mL
50 mM0.0335 mL0.1676 mL0.3351 mL1.6757 mL
100 mM0.0168 mL0.0838 mL0.1676 mL0.8379 mL

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