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MN58b
🥰Excellent
Catalog No. T12085Cas No. 203192-01-2
MN58b is a selective inhibitor of choline kinase α (CHKα).
MN58b
🥰Excellent
Purity: 97.23%
Catalog No. T12085Cas No. 203192-01-2
MN58b is a selective inhibitor of choline kinase α (CHKα).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $311 | In Stock | |
| 5 mg | $759 | In Stock | |
| 10 mg | $987 | In Stock | |
| 25 mg | $1,550 | In Stock | |
| 50 mg | $1,980 | In Stock | |
| 100 mg | $2,790 | In Stock |
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Purity:97.23%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MN58b is a selective inhibitor of choline kinase α (CHKα). |
| In vitro | MN58b (1-5 μM; 72 hours; SK-PC-1, Suit2 008, IMIM-PC2, and RWP-1 cells) has a marked effect on colony formation at 1 μM, and growth is completely abolished at 5 μM in all the cell lines[1] |
| In vivo | MN58b treatment significantly decreases phosphomonoesters in both HT29 and MDA-MB-231 xenografts. Phosphocholine levels are found to correlate with choline kinase activities[2]. |
| Molecular Weight | 640.49 |
| Formula | C32H40Br2N4 |
| Cas No. | 203192-01-2 |
| Smiles | [Br-].[Br-].CN(C)c1cc[n+](Cc2ccc(CCCCc3ccc(C[n+]4ccc(cc4)N(C)C)cc3)cc2)cc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 6.41 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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