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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $46 | In Stock | |
5 mg | $80 | In Stock | |
10 mg | $128 | In Stock | |
25 mg | $263 | In Stock | |
50 mg | $422 | In Stock | |
100 mg | $678 | In Stock |
Description | Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. |
In vitro | Sugammadex has a high affinity for Pipecuronium bromide. As Pipecuronium bromide is approximately 6 to 7 times more potent than Rocuronium, Sugammadex achieves a more effective molecular blockade compared to Rocuronium [3]. |
In vivo | Sugammadex adequately and rapidly reverses pipecuronium bromide induced moderate NMB during sevoflurane anesthesia. Once the train-of-four count has spontaneously returned to 2 responses following pipecuronium bromide administration, a dose of 2.0 mg/kg of sugammadex is sufficient to reverse the NMB[2].Carboxymethylated γ-cyclodextrin demonstrates efficient and complete reversal of the Pipecuronium bromide-induced neuromuscular block in an ex vivo rat diaphragm experiment [1]. |
Alias | RGH-1106 |
Molecular Weight | 762.7 |
Formula | C35H62Br2N4O4 |
Cas No. | 52212-02-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 80 mg/mL (104.89 mM) DMSO: 120 mg/mL (157.34 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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