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Raclopride

🥰Excellent
Catalog No. T7635Cas No. 84225-95-6

Raclopride is a selective antagonist of dopamine D2/D3 receptor.

Raclopride

Raclopride

🥰Excellent
Purity: 99.17%
Catalog No. T7635Cas No. 84225-95-6
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
Pack SizePriceAvailabilityQuantity
5 mg42 €In Stock
10 mg58 €In Stock
25 mg119 €In Stock
50 mg208 €In Stock
100 mg313 €In Stock
1 mL x 10 mM (in DMSO)47 €In Stock
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Purity:99.17%
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Product Introduction

Bioactivity
Description
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
Targets&IC50
D2:1.8nM, D3:3.5nM, D1:18,000 nM, D4:2,400nM
In vivo
Raclopride passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington's disease[1]
Chemical Properties
Molecular Weight347.24
FormulaC15H20Cl2N2O3
Cas No.84225-95-6
SmilesCCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC
Relative Density.1.288 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (287.99 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8799 mL14.3993 mL28.7985 mL143.9926 mL
5 mM0.5760 mL2.8799 mL5.7597 mL28.7985 mL
10 mM0.2880 mL1.4399 mL2.8799 mL14.3993 mL
20 mM0.1440 mL0.7200 mL1.4399 mL7.1996 mL
50 mM0.0576 mL0.2880 mL0.5760 mL2.8799 mL
100 mM0.0288 mL0.1440 mL0.2880 mL1.4399 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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