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Ro60-0175

Catalog No. T39161 CAS 169675-08-5

Synonyms: Ro60-0175

Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B receptor agonist and a 5-hydroxytryptamine 2C receptor agonist.

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Ro60-0175, CAS 169675-08-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 98.00
5 mg	In stock	$ 263.00
10 mg	In stock	$ 422.00
25 mg	In stock	$ 689.00
50 mg	In stock	$ 981.00
100 mg	In stock	$ 1,350.00
500 mg	In stock	$ 2,680.00
1 mL * 10 mM (in DMSO)	In stock	$ 393.00

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Purity: 97.09%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B receptor agonist and a 5-hydroxytryptamine 2C receptor agonist.
In vivo	Ghrelin administration increased operant responding for food reward and that this effect was attenuated by pre-administration of intraperitoneal or ventral tegmental area Ro60-0175.

Synonyms	Ro60-0175
Molecular Weight	226.68
Formula	C11H12ClFN2
CAS No.	169675-08-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 120 mg/mL (529.38 mM), Sonification is recommended.

References and Literature

1. Howell E, et al. Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT2c) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward. Int J Mol Sci. 2019 Feb 19;20(4):889.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Anti-Cancer Compound Library Neuronal Signaling Compound Library Bioactive Compounds Library Max Antidepressant Compound Library Neurotransmitter Receptor Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Viloxazine Liafensine AS19 ST1936 2-Methyl-5-HT 2-Methyl-5-HT hydrochloride SB-200646 Dapoxetine hydrochloride

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ro60-0175 169675-08-5 GPCR/G Protein Neuroscience 5-HT Receptor selective Inhibitor Ro600175 contextual cues inhibit yohimbine 5-hydroxytryptamine Receptor 5-HT2C Ro60 0175 Ro-60-0175 drug-seeking self-administration Serotonin Receptor inhibitor

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