Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pimavanserin tartrate (Nuplazid) is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 43.00 | |
50 mg | In stock | $ 68.00 | |
100 mg | In stock | $ 113.00 | |
200 mg | In stock | $ 146.00 | |
500 mg | In stock | $ 242.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Pimavanserin tartrate (Nuplazid) is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease. |
Targets&IC50 | 5-HT2A:8.7(pIC50) |
In vivo | In rats, Pimavanserin (3 mg/kg, p.o.) attenuates DOI-induced head twitches. In mice, Pimavanserin (3 mg/kg, p.o.) significantly attenuates MK-801-induced hyperactivity. [1] In a rat model of parkinsonian tremor, Pimavanserin (40 mg/kg, i.p.) produces a significant overall reduction of tacrine-induced tremulous jaw movements. [2] |
Synonyms | ACP-103, ACP-103 tartrate, Nuplazid, Pimavanserin |
Molecular Weight | 1005.2 |
Formula | C50H68F2N6O4·C4H6O6 |
CAS No. | 706782-28-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 93 mg/mL (92.5 mM)
DMSO: 93 mg/mL (92.5 mM)
H2O: 92 mg/mL (91.5 mM)
You can also refer to dose conversion for different animals. More
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Pimavanserin tartrate 706782-28-7 GPCR/G Protein Neuroscience 5-HT Receptor Inhibitor Pimavanserin hemitartrate 5-hydroxytryptamine Receptor ACP-103 ACP-103 tartrate ACP-103 Tartrate ACP-103 hemitartrate ACP 103 Tartrate Nuplazid inhibit Pimavanserin ACP103 Tartrate ACP 103 Serotonin Receptor ACP103 Pimavanserin Tartrate inhibitor