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Alosetron hydrochloride
🥰Excellent
Catalog No. T2525Cas No. 122852-69-1
Alias Lotronex, GR 68755X, GR 68755C, GR 68755
Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions.
Alosetron hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T2525Alias Lotronex, GR 68755X, GR 68755C, GR 68755Cas No. 122852-69-1
Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $31 | In Stock | |
| 25 mg | $71 | In Stock | |
| 50 mg | $115 | In Stock | |
| 100 mg | $186 | In Stock | |
| 200 mg | $276 | In Stock |
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CitedSelect Batch
Purity:100%
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions. |
| Alias | Lotronex, GR 68755X, GR 68755C, GR 68755 |
| Molecular Weight | 330.81 |
| Formula | C17H19ClN4O |
| Cas No. | 122852-69-1 |
| Smiles | Cl.Cc1nc[nH]c1CN1CCc2c(C1=O)c1ccccc1n2C |
| Relative Density. | 1.34g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 8.57 mg/mL (25.91 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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