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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $219 | In Stock | |
5 mg | $463 | In Stock | |
10 mg | $683 | In Stock | |
25 mg | $1,070 | In Stock | |
50 mg | $1,450 | In Stock | |
100 mg | $1,950 | In Stock | |
500 mg | $3,890 | In Stock |
Description | cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor. |
In vitro | Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion, decreases caspase-3 activity, and improves cell viability against UV-B irradiation, with no significant effects on IL-6 or IL-8 secretion, caspase-3 activity, or viability in non-irradiated cells in both cell types [1]. |
Alias | cis-UCA, (Z)-Imidazole-4-acrylic acid, (Z)-Urocanic acid, (E)-Urocanic acid, (Z)-3-(1H-Imidazol-5-yl)acrylic acid |
Molecular Weight | 138.12 |
Formula | C6H6N2O2 |
Cas No. | 7699-35-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 40 mg/mL (289.6 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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