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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $41 | In Stock | |
5 mg | $66 | In Stock | |
10 mg | $91 | In Stock | |
25 mg | $188 | In Stock | |
50 mg | $281 | In Stock | |
100 mg | $422 | In Stock | |
1 mL x 10 mM (in DMSO) | $72 | In Stock |
Description | Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors. |
Alias | Gamanil, Amplit, Leo 640, Lopramine |
Molecular Weight | 418.96 |
Formula | C26H27ClN2O |
Cas No. | 23047-25-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 48 mg/mL (114.57 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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