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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $34 | In Stock | |
5 mg | $83 | In Stock | |
10 mg | $136 | In Stock | |
1 mL x 10 mM (in DMSO) | $98 | In Stock |
Description | LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis. |
In vitro | LP-533401 hydrochloride (0.1-1 μM; 3 days) completely inhibited serotonin production in RBL2H3 cells. |
In vivo | LP-533401 hydrochloride (250, 100, 10 mg/kg) prevented and rescued ovariectomized mice from osteoporosis [1]. |
Molecular Weight | 562.94 |
Formula | C27H23ClF4N4O3 |
Cas No. | 1040526-12-2 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 15 mg/mL (26.65 mM) H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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