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LP-533401 hydrochloride
🥰Excellent
Catalog No. T15779Cas No. 1040526-12-2
LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier
that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.
LP-533401 hydrochloride
🥰Excellent
Purity: 98%
Catalog No. T15779Cas No. 1040526-12-2
LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier
that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.
that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $81 | In Stock | |
| 10 mg | $123 | In Stock | |
| 25 mg | Inquiry | In Stock | |
| 1 mL x 10 mM (in DMSO) | $98 | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis. |
| In vitro | LP-533401 hydrochloride (0.1-1 μM; 3 days) completely inhibited serotonin production in RBL2H3 cells. |
| In vivo | LP-533401 hydrochloride (250, 100, 10 mg/kg) prevented and rescued ovariectomized mice from osteoporosis [1]. |
| Molecular Weight | 562.94 |
| Formula | C27H23ClF4N4O3 |
| Cas No. | 1040526-12-2 |
| Smiles | Cl.N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2ccc(cc2)-c2cccc(F)c2)C(F)(F)F)nc(N)n1)C(O)=O |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (26.65 mM), Sonification is recommended. H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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